› 5n7k

X-ray diffraction
2.81Å resolution

Crystal structure of the coiled-coil domain of human tricellulin

Released:
DOI: 10.2210/pdb5n7k/pdb
PDB entry 5n7k coloured by chain, front view.
PDB entry 5n7k coloured by chain, side view.
PDB entry 5n7k coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Schuetz A, Radusheva V, Krug SM, Heinemann U
Ann N Y Acad Sci 1405 147-159 (2017)
PMID: 28661558

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185395 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MARVEL domain-containing protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 115 amino acids
Theoretical weight: 13.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8N4S9 (Residues: 439-551; Coverage: 20%)
Gene names: MARVELD2, TRIC
Sequence domains: Occludin homology domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P3221
Unit cell:
a: 82.621Å b: 82.621Å c: 188.825Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.215 0.242
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Apoptotic Fragmentation of Tricellulin.
Janke et al. (2019)
2 more

1 mention without citation

Structural Features of Tight-Junction Proteins.
Heinemann et al. (2019)