Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-172493 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Interleukin-17A
Molecule details ›
Chains: A, D
Length: 132 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Interleukin-17
Structure domains: Cystine-knot cytokines
Length: 132 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q16552 (Residues: 24-155; Coverage: 100%)
Sequence domains: Interleukin-17
Structure domains: Cystine-knot cytokines
Interleukin-17 receptor A
Molecule details ›
Chains: B, C
Length: 311 amino acids
Theoretical weight: 36.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Structure domains:
Length: 311 amino acids
Theoretical weight: 36.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q96F46 (Residues: 33-320; Coverage: 35%)
Sequence domains:
Structure domains:
Interleukin-17F
Molecule details ›
Chains: E, F
Length: 139 amino acids
Theoretical weight: 15.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Interleukin-17
Structure domains: Cystine-knot cytokines
Length: 139 amino acids
Theoretical weight: 15.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q96PD4 (Residues: 31-163; Coverage: 100%)
Sequence domains: Interleukin-17
Structure domains: Cystine-knot cytokines
