› 5noi

X-ray diffraction
2.4Å resolution

human Robo2 extracellular domains 4-5

Released:
DOI: 10.2210/pdb5noi/pdb
PDB entry 5noi coloured by chain, front view.
PDB entry 5noi coloured by chain, side view.
PDB entry 5noi coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Robo Ig4 Is a Dimerization Domain.
Yom-Tov G, Barak R, Matalon O, Barda-Saad M, Guez-Haddad J, Opatowsky Y
J Mol Biol 429 3606-3616 (2017)
PMID: 29017837

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190781 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Roundabout homolog 2 Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 21.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9HCK4 (Residues: 311-509; Coverage: 15%)
Gene names: KIAA1568, ROBO2
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: I4122
Unit cell:
a: 99.749Å b: 99.749Å c: 123.465Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.237 0.267
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

The Role of the Slit/Robo Signaling Pathway.
Tong et al. (2019)
4 more