Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- GPCR, family 2, glucagon-like peptide-1 receptor
- GPCR, family 2, extracellular hormone receptor domain
- GPCR, family 2, glucagon-like peptide-1/glucagon receptor
- GPCR family 2, extracellular hormone receptor domain superfamily
- Glucagon
- Glucagon/GIP/secretin/VIP
- GPCR, family 2, secretin-like, conserved site
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Glucagon-like peptide 1 receptor and Glucagon (preferred)
PDBe Complex ID:
PDB-CPX-134156 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glucagon-like peptide 1 receptor
Molecule details ›
Chains: A, C
Length: 116 amino acids
Theoretical weight: 13.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Hormone receptor domain
Length: 116 amino acids
Theoretical weight: 13.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P43220 (Residues: 24-139; Coverage: 26%)
Sequence domains: Hormone receptor domain
Glucagon-like peptide 1(7-37)
Molecule details ›
Chains: B, D
Length: 31 amino acids
Theoretical weight: 3.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Sequence domains: Peptide hormone
Length: 31 amino acids
Theoretical weight: 3.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P01275 (Residues: 98-128; Coverage: 19%)
Sequence domains: Peptide hormone
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU FR-X
Spacegroup:
P21
Expression systems:
- Escherichia coli
- Not provided
