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Hybrid

STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT OF CRYSTAL FORM II

Released:
DOI: 10.2210/pdb5pti/pdb
PDB entry 5pti coloured by chain, front view.
PDB entry 5pti coloured by chain, side view.
PDB entry 5pti coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II.
Wlodawer A, Walter J, Huber R, Sjölin L
J Mol Biol 180 301-29 (1984)
PMID: 6210373

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133749 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pancreatic trypsin inhibitor Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.53 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P00974 (Residues: 36-93; Coverage: 73%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

3 bound ligands:
Ligand PO4 1 x PO4
Ligand UNX 1 x UNX
Ligand DOD 63 x DOD
No modified residues

Experiments and Validation Details

Experimental Method: Neutron Diffraction, X-ray diffraction
Spacegroup: P212121
Unit cell:
a: 74.1Å b: 23.4Å c: 28.9Å
α: 90° β: 90° γ: 90°
Expression system: Not provided

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Citations

18 review citations

The mammalian low-density lipoprotein receptor family.
Hussain et al. (1999)
17 more

96 mentions without citation

Water Determines the Structure and Dynamics of Proteins.
Bellissent-Funel et al. (2016)
95 more