Function and Biology Details
Reaction catalysed:
Formylmethanofuran + H(2)O + 2 oxidized ferredoxin [iron-sulfur] cluster = CO(2) + methanofuran + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- 4Fe-4S ferredoxin-type, iron-sulphur binding domain
- 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
- Metal-dependent hydrolase, composite domain superfamily
- Formylmethanofuran dehydrogenase, subunit A
- Glutamate synthase, alpha subunit, C-terminal domain superfamily
- Formylmethanofuran dehydrogenase subunit C
- Formylmethanofuran dehydrogenase, subunit B
- Polyferredoxin MvhB-like
7 more domains
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-130754 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Amidohydrolase 3 domain-containing protein
Molecule details ›
Chains: A, I
Length: 569 amino acids
Theoretical weight: 62.81 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
Sequence domains: Amidohydrolase family
Length: 569 amino acids
Theoretical weight: 62.81 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
- Canonical:
O74030 (Residues: 1-569; Coverage: 100%)
Sequence domains: Amidohydrolase family
Molybdopterin oxidoreductase domain-containing protein
Molecule details ›
Chains: B, J
Length: 432 amino acids
Theoretical weight: 48.41 KDa
Source organism: Methanothermobacter sp. CaT2
UniProt:
Sequence domains: Molybdopterin oxidoreductase
Length: 432 amino acids
Theoretical weight: 48.41 KDa
Source organism: Methanothermobacter sp. CaT2
UniProt:
- Canonical: T2GJQ6 (Residues: 1-432; Coverage: 100%)
Sequence domains: Molybdopterin oxidoreductase
Tungsten-containing formylmethanofuran dehydrogenase 2 subunit C
Molecule details ›
Chains: C, K
Length: 270 amino acids
Theoretical weight: 28.61 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
Length: 270 amino acids
Theoretical weight: 28.61 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
- Canonical: O74031 (Residues: 1-270; Coverage: 100%)
Molybdopterin dinucleotide-binding domain-containing protein
Molecule details ›
Chains: D, L
Length: 130 amino acids
Theoretical weight: 14.41 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
Sequence domains: Molydopterin dinucleotide binding domain
Structure domains: Barwin-like endoglucanases
Length: 130 amino acids
Theoretical weight: 14.41 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
- Canonical: O74029 (Residues: 1-130; Coverage: 100%)
Sequence domains: Molydopterin dinucleotide binding domain
Structure domains: Barwin-like endoglucanases
4Fe-4S ferredoxin-type domain-containing protein
Molecule details ›
Chains: F, N
Length: 349 amino acids
Theoretical weight: 38.62 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
Sequence domains:
Length: 349 amino acids
Theoretical weight: 38.62 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
- Canonical: O74028 (Residues: 1-349; Coverage: 100%)
Sequence domains:
4Fe-4S ferredoxin-type domain-containing protein
Molecule details ›
Chains: G, P
Length: 82 amino acids
Theoretical weight: 8.56 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
Sequence domains: 4Fe-4S dicluster domain
Length: 82 amino acids
Theoretical weight: 8.56 KDa
Source organism: Methanothermobacter wolfeii
UniProt:
- Canonical: Q1MVD4 (Residues: 1-82; Coverage: 100%)
Sequence domains: 4Fe-4S dicluster domain
