› 5tdq

X-ray diffraction
2.49Å resolution

Crystal Structure of the GOLD domain of ACBD3

Released:
DOI: 10.2210/pdb5tdq/pdb
PDB entry 5tdq coloured by chain, front view.
PDB entry 5tdq coloured by chain, side view.
PDB entry 5tdq coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3.
McPhail JA, Ottosen EH, Jenkins ML, Burke JE
Structure 25 121-131 (2017)
PMID: 27989622

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190584 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Golgi resident protein GCP60, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 166 amino acids
Theoretical weight: 19.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H3P7 (Residues: 367-528; Coverage: 31%)
Gene names: ACBD3, GCP60, GOCAP1, GOLPH1
Sequence domains: Golgi-dynamics membrane-trafficking

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P3121
Unit cell:
a: 55.51Å b: 55.51Å c: 140.15Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.238 0.262
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery.
Masson et al. (2017)
8 more

1 mention without citation

Acyl-CoA-Binding Domain-Containing 3 (ACBD3; PAP7; GCP60): A Multi-Functional Membrane Domain Organizer.
Yue et al. (2019)