5ty4

Electron crystallography
2.9Å resolution

MicroED structure of a complex between monomeric TGF-b and its receptor, TbRII, at 2.9 A resolution

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-153365 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
TGF-beta receptor type-2 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P37173 (Residues: 47-149; Coverage: 19%)
Gene name: TGFBR2
Sequence domains: Transforming growth factor beta receptor 2 ectodomain
Structure domains: CD59
Transforming growth factor beta-2 Chain: B
Molecule details ›
Chain: B
Length: 97 amino acids
Theoretical weight: 11.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61812 (Residues: 317-413; Coverage: 25%)
Gene name: TGFB2
Sequence domains: Transforming growth factor beta like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.9Å
Relevant EMDB volumes: EMD-8472
Expression system: Escherichia coli