Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140301 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Interleukin-3 receptor subunit alpha
Molecule details ›
Chain: G
Length: 288 amino acids
Theoretical weight: 33.25 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 288 amino acids
Theoretical weight: 33.25 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P26951 (Residues: 20-307; Coverage: 80%)
Sequence domains:
Structure domains:
Interleukin-3
Molecule details ›
Chain: I
Length: 122 amino acids
Theoretical weight: 13.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Interleukin-3
Structure domains: Growth Hormone; Chain: A;
Length: 122 amino acids
Theoretical weight: 13.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P08700 (Residues: 31-152; Coverage: 92%)
Sequence domains: Interleukin-3
Structure domains: Growth Hormone; Chain: A;
Ligands and Environments
Experiments and Validation Details
X-ray source:
AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup:
P61
Expression systems:
- Spodoptera frugiperda
- Escherichia coli
