5v8w

X-ray diffraction
2.1Å resolution

Crystal structure of human Integrator IntS9-IntS11 CTD complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178315 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrator complex subunit 9 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 78 amino acids
Theoretical weight: 9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NV88 (Residues: 581-658; Coverage: 12%)
Gene names: INTS9, RC74
Sequence domains: Integrator IntS9, C-terminal domain
Integrator complex subunit 11 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 114 amino acids
Theoretical weight: 12.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5TA45 (Residues: 491-600; Coverage: 18%)
Gene names: CPSF3L, INTS11, RC68
Sequence domains: Integrator IntS11, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P21
Unit cell:
a: 63.01Å b: 67.78Å c: 98.585Å
α: 90° β: 100.65° γ: 90°
R-values:
R R work R free
0.169 0.166 0.22
Expression system: Escherichia coli