5vem

X-ray diffraction
2.6Å resolution

Human ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-193812 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 416 amino acids
Theoretical weight: 48.19 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9UJA9 (Residues: 25-430; Coverage: 90%)
Gene names: ENPP5, UNQ550/PRO1107
Sequence domains: Type I phosphodiesterase / nucleotide pyrophosphatase

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, FUC
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P31
Unit cell:
a: 109.411Å b: 109.411Å c: 134.82Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.197 0.196 0.227
Expression system: Spodoptera frugiperda