› 5vrf

Electron Microscopy
4.1Å resolution

CryoEM Structure of the Zinc Transporter YiiP from helical crystals

Released:
DOI: 10.2210/pdb5vrf/pdb
PDB entry 5vrf coloured by chain, front view.
PDB entry 5vrf coloured by chain, side view.
PDB entry 5vrf coloured by chain, top view.
Source organism: Shewanella oneidensis MR-1
Primary publication:
Structural basis for the alternating access mechanism of the cation diffusion facilitator YiiP.
Lopez-Redondo ML, Coudray N, Zhang Z, Alexopoulos J, Stokes DL
Proc Natl Acad Sci U S A 115 3042-3047 (2018)
PMID: 29507252
Related structures: EMD-8728

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184310 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation-efflux pump FieF Chains: A, B
Molecule details ›
Chains: A, B
Length: 296 amino acids
Theoretical weight: 32.49 KDa
Source organism: Shewanella oneidensis MR-1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8E919 (Residues: 1-296; Coverage: 100%)
Gene names: SO_4475, fieF, yiiP
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 8 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.1Å
Relevant EMDB volumes: EMD-8728
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Zinc transporters and their functional integration in mammalian cells.
Kambe et al. (2021)
3 more

15 mentions without citation

Ins and Outs: Recent Advancements in Membrane Protein-Mediated Prokaryotic Ferrous Iron Transport.
Brown et al. (2021)
14 more