Function and Biology Details
Reaction catalysed:
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210604 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Dipeptidyl peptidase 4
Molecule details ›
Chains: A, B, C, D
Length: 739 amino acids
Theoretical weight: 85.53 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 739 amino acids
Theoretical weight: 85.53 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
- Canonical:
P14740 (Residues: 37-767; Coverage: 95%)
Sequence domains:
- Dipeptidyl peptidase IV (DPP IV) low complexity region
- Dipeptidyl peptidase IV (DPP IV) N-terminal region
- Prolyl oligopeptidase family
