Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-154626 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Serine/threonine-protein kinase mTOR
Molecule details ›
Target of rapamycin complex subunit LST8
Molecule details ›
Chains: C, D
Length: 328 amino acids
Theoretical weight: 36.05 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Length: 328 amino acids
Theoretical weight: 36.05 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9BVC4 (Residues: 1-326; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Proline-rich AKT1 substrate 1
Molecule details ›
Chains: O, P
Length: 98 amino acids
Theoretical weight: 10.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Proline-rich AKT1 substrate 1
Length: 98 amino acids
Theoretical weight: 10.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q96B36 (Residues: 114-207; Coverage: 37%)
Sequence domains: Proline-rich AKT1 substrate 1
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-C
Expression systems:
- Homo sapiens
- Escherichia coli
