5wuv

X-ray diffraction
1.95Å resolution

Crystal structure of Certolizumab Fab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213942 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Thermus thermophilus shuttle vector pTRH1T
Structure domains: Immunoglobulins
heavy chain Chain: H
Molecule details ›
Chain: H
Length: 224 amino acids
Theoretical weight: 23.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpB1GAP
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P212121
Unit cell:
a: 58.33Å b: 63.696Å c: 161.415Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.149 0.148 0.179
Expression systems:
  • Escherichia coli-Thermus thermophilus shuttle vector pTRH1T
  • Escherichia coli-Pichia pastoris shuttle vector pPpB1GAP