Function and Biology Details
Reaction catalysed:
ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130036 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Eukaryotic translation initiation factor 4E type 2
Molecule details ›
Chain: A
Length: 190 amino acids
Theoretical weight: 21.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Eukaryotic initiation factor 4E
Length: 190 amino acids
Theoretical weight: 21.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O60573 (Residues: 45-234; Coverage: 78%)
Sequence domains: Eukaryotic initiation factor 4E
Threonine--tRNA ligase 1, cytoplasmic
Molecule details ›
Chain: B
Length: 45 amino acids
Theoretical weight: 5.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 45 amino acids
Theoretical weight: 5.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P26639 (Residues: 30-74; Coverage: 6%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PAL/PLS BEAMLINE 5C (4A)
Spacegroup:
P212121
Expression system: Escherichia coli
