› 5xmy

X-ray diffraction
1.7Å resolution

Crystal structure of TAF3 PHD finger bound to H3K4me3Q5ser

Released:
DOI: 10.2210/pdb5xmy/pdb
PDB entry 5xmy coloured by chain, front view.
PDB entry 5xmy coloured by chain, side view.
PDB entry 5xmy coloured by chain, top view.
Source organisms:
Entry authors: Zhao S, Zhang B, Li H

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166312 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transcription initiation factor TFIID subunit 3 Chains: A, C
Molecule details ›
Chains: A, C
Length: 63 amino acids
Theoretical weight: 7.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5VWG9 (Residues: 853-915; Coverage: 7%)
Gene name: TAF3
Sequence domains: PHD-finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
Histone peptide H3(1-15)K4me3Q5ser Chains: D, P
Molecule details ›
Chains: D, P
Length: 7 amino acids
Theoretical weight: 819 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
1 modified residue:
Ligand M3L 2 x M3L

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P21
Unit cell:
a: 26.982Å b: 48.096Å c: 52.7Å
α: 90° β: 98.16° γ: 90°
R-values:
R R work R free
0.184 0.182 0.221
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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