Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Ku70/Ku80 beta-barrel domain
- SPOC-like, C-terminal domain superfamily
- von Willebrand factor A-like domain superfamily
- Phosphatidylinositol 3-/4-kinase, catalytic domain
- Armadillo-type fold
- FATC domain
- Phosphatidylinositol 3/4-kinase, conserved site
- DNA-dependent protein kinase catalytic subunit, CC3
16 more domains
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-119426 (preferred)
Entry contents:
4 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (6 distinct):
X-ray repair cross-complementing protein 6
Molecule details ›
Chain: A
Length: 501 amino acids
Theoretical weight: 57.62 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 501 amino acids
Theoretical weight: 57.62 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P12956 (Residues: 34-534; Coverage: 82%)
Sequence domains:
X-ray repair cross-complementing protein 5
Molecule details ›
Chain: B
Length: 536 amino acids
Theoretical weight: 60.97 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 536 amino acids
Theoretical weight: 60.97 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P13010 (Residues: 6-541; Coverage: 73%)
Sequence domains:
DNA-dependent protein kinase catalytic subunit
Molecule details ›
Chain: C
Length: 4119 amino acids
Theoretical weight: 468.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 4119 amino acids
Theoretical weight: 468.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P78527 (Residues: 10-4128; Coverage: 100%)
Sequence domains:
