› 5z8s

X-ray diffraction
1.97Å resolution

Human Mitochondrial ferritin mutant - C102A/C130A/E27C/E61C/E62C

Released:
DOI: 10.2210/pdb5z8s/pdb
PDB entry 5z8s coloured by chain, front view.
PDB entry 5z8s coloured by chain, side view.
PDB entry 5z8s coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.
Zang J, Zheng B, Zhang X, Arosio P, Zhao G
J Nanobiotechnology 17 79 (2019)
PMID: 31277668

Function and Biology Details

Reaction catalysed: 
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185388 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 20.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8N4E7 (Residues: 61-242; Coverage: 75%)
Gene name: FTMT
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

1 bound ligand:
Ligand AU 2 x AU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: F432
Unit cell:
a: 182.736Å b: 182.736Å c: 182.736Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.166 0.2
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Ferritin: A Promising Nanoreactor and Nanocarrier for Bionanotechnology.
Mohanty et al. (2022)
3 other articles