Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- P-loop containing nucleoside triphosphate hydrolase
- Origin recognition complex subunit 4
- Origin recognition complex, subunit 2
- AAA+ ATPase domain
- Bromo adjacent homology (BAH) domain
- Origin recognition complex, subunit 6
- Origin recognition complex, subunit 6, fungi
- Origin recognition complex subunit 5, C-terminal
8 more domains
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
Assembly name:
Origin recognition complex and DNA (preferred)
PDBe Complex ID:
PDB-CPX-119528 (preferred)
Entry contents:
6 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (8 distinct):
Origin recognition complex subunit 1
Molecule details ›
Chain: A
Length: 914 amino acids
Theoretical weight: 104.55 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 914 amino acids
Theoretical weight: 104.55 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
P54784 (Residues: 1-914; Coverage: 100%)
Sequence domains:
Origin recognition complex subunit 2
Molecule details ›
Chain: B
Length: 620 amino acids
Theoretical weight: 71.34 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Origin recognition complex subunit 2
Length: 620 amino acids
Theoretical weight: 71.34 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P32833 (Residues: 1-620; Coverage: 100%)
Sequence domains: Origin recognition complex subunit 2
Origin recognition complex subunit 3
Molecule details ›
Chain: C
Length: 616 amino acids
Theoretical weight: 72.16 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Origin recognition complex winged helix C-terminal
Length: 616 amino acids
Theoretical weight: 72.16 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P54790 (Residues: 1-616; Coverage: 100%)
Sequence domains: Origin recognition complex winged helix C-terminal
Origin recognition complex subunit 4
Molecule details ›
Chain: D
Length: 529 amino acids
Theoretical weight: 60.77 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Origin recognition complex (ORC) subunit 4 C-terminus
Length: 529 amino acids
Theoretical weight: 60.77 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P54791 (Residues: 1-529; Coverage: 100%)
Sequence domains: Origin recognition complex (ORC) subunit 4 C-terminus
Origin recognition complex subunit 5
Molecule details ›
Chain: E
Length: 479 amino acids
Theoretical weight: 55.35 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 479 amino acids
Theoretical weight: 55.35 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P50874 (Residues: 1-479; Coverage: 100%)
Sequence domains:
Origin recognition complex subunit 6
Molecule details ›
Chain: F
Length: 435 amino acids
Theoretical weight: 50.37 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Origin recognition complex subunit 6 (ORC6)
Length: 435 amino acids
Theoretical weight: 50.37 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P38826 (Residues: 1-435; Coverage: 100%)
Sequence domains: Origin recognition complex subunit 6 (ORC6)
