› 6a9p

X-ray diffraction
2.51Å resolution

Crystal structure of the human glial fibrillary acidic protein 1B domain

Released:
DOI: 10.2210/pdb6a9p/pdb
PDB entry 6a9p coloured by chain, front view.
PDB entry 6a9p coloured by chain, side view.
PDB entry 6a9p coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human glial fibrillary acidic protein 1B domain.
Kim B, Kim S, Jin MS
Biochem Biophys Res Commun 503 2899-2905 (2018)
PMID: 30126635

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146855 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glial fibrillary acidic protein Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 106 amino acids
Theoretical weight: 12.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P14136 (Residues: 110-213; Coverage: 24%)
Gene name: GFAP
Sequence domains: Intermediate filament protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P1
Unit cell:
a: 23.588Å b: 106.158Å c: 113.225Å
α: 77.56° β: 90.14° γ: 83.8°
R-values:
R R work R free
0.271 0.269 0.311
Expression system: Escherichia coli

Quick links

Citations

2 review citations

GFAP at 50.
Messing et al. (2020)
1 more

5 mentions without citation

Recent insight into intermediate filament structure.
Eldirany et al. (2021)
4 more