› 6apn

X-ray diffraction
2.22Å resolution

HLA-A*0201 single chain trimer with HPV.16 E7 peptide LLMGTLGIV

Released:
DOI: 10.2210/pdb6apn/pdb
PDB entry 6apn coloured by chain, front view.
PDB entry 6apn coloured by chain, side view.
PDB entry 6apn coloured by chain, top view.
Source organisms:
Entry author: Finton KAK

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136594 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-2-microglobulin; HLA class I histocompatibility antigen, A alpha chain; Protein E7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 446 amino acids
Theoretical weight: 50.09 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: P03129 (Residues: 82-90; Coverage: 9%)
  • Canonical: P61769 (Residues: 16-119; Coverage: 100%)
  • Canonical: P04439 (Residues: 26-305; Coverage: 81%)
Gene names: B2M, CDABP0092, E7, HDCMA22P, HLA-A, HLAA
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P21
Unit cell:
a: 50.363Å b: 65.094Å c: 130.321Å
α: 90° β: 96.25° γ: 90°
R-values:
R R work R free
0.216 0.213 0.26
Expression system: Homo sapiens

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