› 6aw2

X-ray diffraction
2.68Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124794 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Carcinoembryonic antigen-related cell adhesion molecule 1 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13688 (Residues: 34-141; Coverage: 22%)
Gene names: BGP, BGP1, CEACAM1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
SabA N-terminal extracellular adhesion domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 439 amino acids
Theoretical weight: 47.03 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: H6A3H4 (Residues: 38-462; Coverage: 69%)
Gene name: hopQ
Sequence domains: SabA N-terminal extracellular adhesion domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P2221
Unit cell:
a: 39.67Å b: 103.077Å c: 112.881Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.234 0.277
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

Helicobacter pylori Virulence Factors-Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment.
Baj et al. (2020)
8 more

3 mentions without citation

CEACAM1 structure and function in immunity and its therapeutic implications.
Kim et al. (2019)
2 more