Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130062 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mitotic spindle assembly checkpoint protein MAD2B
Molecule details ›
Chains: A, C, E, G
Length: 227 amino acids
Theoretical weight: 26.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: HORMA domain
Length: 227 amino acids
Theoretical weight: 26.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q9UI95 (Residues: 1-211; Coverage: 100%)
Sequence domains: HORMA domain
DNA polymerase zeta catalytic subunit
Molecule details ›
Chains: B, D, F, H
Length: 28 amino acids
Theoretical weight: 3.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Length: 28 amino acids
Theoretical weight: 3.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: O60673 (Residues: 1987-2014; Coverage: 1%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
CHESS BEAMLINE F1
Spacegroup:
P3121
Expression system: Escherichia coli BL21
