Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- WD40 repeat
- WD40/YVTN repeat-like-containing domain superfamily
- WD40-repeat-containing domain superfamily
- Pre-mRNA 3' end processing protein Pfs2-like
- Homing endonuclease
- Cleavage/polyadenylation specificity factor, A subunit, C-terminal
- Cleavage/polyadenylation specificity factor, A subunit, N-terminal
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171233 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cleavage and polyadenylation specificity factor subunit 1
Molecule details ›
Chain: A
Length: 1443 amino acids
Theoretical weight: 161.07 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 1443 amino acids
Theoretical weight: 161.07 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q10570 (Residues: 1-1443; Coverage: 100%)
Sequence domains:
pre-mRNA 3' end processing protein WDR33
Molecule details ›
Chain: B
Length: 587 amino acids
Theoretical weight: 67.55 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: WD domain, G-beta repeat
Length: 587 amino acids
Theoretical weight: 67.55 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q9C0J8 (Residues: 1-572; Coverage: 43%)
Sequence domains: WD domain, G-beta repeat
