› 6bxv

X-ray diffraction
1.1Å resolution

SYSSYGQS from low-complexity domain of FUS, residues 54-61

Released:
DOI: 10.2210/pdb6bxv/pdb
PDB entry 6bxv coloured by chain, front view.
PDB entry 6bxv coloured by chain, side view.
PDB entry 6bxv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks.
Hughes MP, Sawaya MR, Boyer DR, Goldschmidt L, Rodriguez JA, Cascio D, Chong L, Gonen T, Eisenberg DS
Science 359 698-701 (2018)
PMID: 29439243

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-binding protein FUS Chain: A
Molecule details ›
Chain: A
Length: 8 amino acids
Theoretical weight: 878 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P35637 (Residues: 54-61; Coverage: 2%)
Gene names: FUS, TLS

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: C2
Unit cell:
a: 49.58Å b: 4.785Å c: 21.812Å
α: 90° β: 95.46° γ: 90°
R-values:
R R work R free
0.138 0.137 0.148
Expression system: Not provided

Quick links

Citations

79 review citations

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates.
Alberti et al. (2019)
78 more

3 mentions without citation

Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks.
Hughes et al. (2018)
2 more