› 6byb

X-ray diffraction
1.74Å resolution

Crystal structure of L3MBTL1 MBT Domain with MBK14970

Released:
DOI: 10.2210/pdb6byb/pdb
PDB entry 6byb coloured by chain, front view.
PDB entry 6byb coloured by chain, side view.
PDB entry 6byb coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: DONG A, DOBROVETSKY E, NICHOLSON B, COX C, FISCHER C, ARMACOST K, SANDERS J, Bountra C, Arrowsmith CH, Edwards AM, BROWN PJ, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195224 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lethal(3)malignant brain tumor-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 37.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y468 (Residues: 268-590; Coverage: 39%)
Gene names: KIAA0681, L3MBT, L3MBTL, L3MBTL1
Sequence domains: mbt repeat
Structure domains: SH3 type barrels.

Ligands and Environments

3 bound ligands:
Ligand EC7 1 x EC7
Ligand EDO 8 x EDO
Ligand UNX 13 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21212
Unit cell:
a: 85.88Å b: 93.166Å c: 58.444Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.2 0.222
Expression system: Escherichia coli BL21(DE3)

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