› 6bzp

Electron crystallography
1.1Å resolution

STGGYG from low-complexity domain of FUS, residues 77-82

Released:
DOI: 10.2210/pdb6bzp/pdb
PDB entry 6bzp coloured by chain, front view.
PDB entry 6bzp coloured by chain, side view.
PDB entry 6bzp coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks.
Hughes MP, Sawaya MR, Boyer DR, Goldschmidt L, Rodriguez JA, Cascio D, Chong L, Gonen T, Eisenberg DS
Science 359 698-701 (2018)
PMID: 29439243

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152982 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-binding protein FUS Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 amino acids
Theoretical weight: 541 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P35637 (Residues: 77-82; Coverage: 1%)
Gene names: FUS, TLS

Ligands and Environments

1 bound ligand:
Ligand TOE 1 x TOE
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 1.1Å
Expression system: Not provided

Quick links

Citations

78 review citations

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates.
Alberti et al. (2019)
77 more

6 mentions without citation

Electron Diffraction of 3D Molecular Crystals.
Saha et al. (2022)
5 more