Function and Biology Details
Reaction catalysed:
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|- bonds) as well as an endopeptidase.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Pro-cathepsin H (preferred)
PDBe Complex ID:
PDB-CPX-140729 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Pro-cathepsin H
Molecule details ›
Chain: A
Length: 335 amino acids
Theoretical weight: 37.45 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains: Cysteine proteinases
Length: 335 amino acids
Theoretical weight: 37.45 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P09668 (Residues: 1-335; Coverage: 100%)
Sequence domains:
Structure domains: Cysteine proteinases
Ligands and Environments
1 modified residue:
Experiments and Validation Details
X-ray source:
APS BEAMLINE 22-ID
Spacegroup:
P3121
Expression system: Spodoptera frugiperda
