PDB 6d56 structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

GTP + H(2)O = GDP + phosphate

Biochemical function:

GTP binding

Biological process:

signal transduction

Cellular component:

membrane

Sequence domains:

2 more domains

Structure analysis Details

Assembly composition:

hetero trimer (preferred)

Assembly name:

Son of sevenless homolog 1 and GTPase HRas, N-terminally processed (preferred)

PDBe Complex ID:

PDB-CPX-133957 (preferred)

Entry contents:

3 distinct polypeptide molecules

Macromolecules (3 distinct):

GTPase HRas, N-terminally processed Chain: A

Molecule details ›

Chain: A
Length: 167 amino acids
Theoretical weight: 18.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

Canonical: P01112 (Residues: 1-166; Coverage: 88%)

Gene names: HRAS, HRAS1
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Son of sevenless homolog 1 Chain: B

Molecule details ›

Chain: B
Length: 482 amino acids
Theoretical weight: 56.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

Canonical: Q07889 (Residues: 566-1046; Coverage: 36%)

Gene name: SOS1
Sequence domains:

Structure domains:

GTPase HRas, N-terminally processed Chain: C

Molecule details ›

Chain: C
Length: 167 amino acids
Theoretical weight: 18.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt: