› 6dlv

Electron Microscopy
10.1Å resolution

Cryo-EM of the GTP-bound human dynamin-1 polymer assembled on the membrane in the super constricted state

Released:
DOI: 10.2210/pdb6dlv/pdb
PDB entry 6dlv coloured by chain, front view.
PDB entry 6dlv coloured by chain, side view.
PDB entry 6dlv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Cryo-EM of the dynamin polymer assembled on lipid membrane.
Kong L, Sochacki KA, Wang H, Fang S, Canagarajah B, Kehr AD, Rice WJ, Strub MP, Taraska JW, Hinshaw JE
Nature 560 258-262 (2018)
PMID: 30069048
Related structures: EMD-7958

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dynamin-1 Chains: b, c, f, g
Molecule details ›
Chains: b, c, f, g
Length: 748 amino acids
Theoretical weight: 85.86 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q05193 (Residues: 1-748; Coverage: 87%)
Gene names: DNM, DNM1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 10.1Å
Relevant EMDB volumes: EMD-7958
Expression system: Trichoplusia ni

Quick links

Citations

8 review citations

Function and regulation of the divisome for mitochondrial fission.
Kraus et al. (2021)
7 more

4 mentions without citation

Cryo-EM of the dynamin polymer assembled on lipid membrane.
Kong et al. (2018)
3 more