› 6dm4

X-ray diffraction
1.9Å resolution

Crystal structure of the SH2 domain from RavO (Lpg1129) from Legionella pneumophila in complex with Homo sapiens Shc1 phospho-Tyr317 peptide

Released:
DOI: 10.2210/pdb6dm4/pdb
PDB entry 6dm4 coloured by chain, front view.
PDB entry 6dm4 coloured by chain, side view.
PDB entry 6dm4 coloured by chain, top view.
Source organisms:
Entry authors: Stogios PJ, Evdokimova E, Di Leo R, Kaneko T, Li S, Savchenko A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero trimer
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151422 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RavO Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 120 amino acids
Theoretical weight: 13.77 KDa
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5ZWF6 (Residues: 225-344; Coverage: 23%)
Gene name: lpg1129
SHC-transforming protein 1 Chains: E, G, H
Molecule details ›
Chains: E, G, H
Length: 7 amino acids
Theoretical weight: 886 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P29353 (Residues: 425-431; Coverage: 1%)
Gene names: SHC, SHC1, SHCA

Ligands and Environments

1 bound ligand:
Ligand SO4 6 x SO4
1 modified residue:
Ligand PTR 3 x PTR

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P1
Unit cell:
a: 44.454Å b: 45.035Å c: 74.748Å
α: 72.6° β: 90.14° γ: 77.55°
R-values:
R R work R free
0.185 0.182 0.23
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links