Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + N-terminal-(A,P,S)PK-[protein] = S-adenosyl-L-homocysteine + N-terminal-N-methyl-N-(A,P,S)PK-[protein]
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148442 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
N-terminal Xaa-Pro-Lys N-methyltransferase 2
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 25.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: AdoMet dependent proline di-methyltransferase
Structure domains: Vaccinia Virus protein VP39
Length: 222 amino acids
Theoretical weight: 25.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q5VVY1 (Residues: 58-278; Coverage: 78%)
Sequence domains: AdoMet dependent proline di-methyltransferase
Structure domains: Vaccinia Virus protein VP39
Regulator of chromosome condensation
Molecule details ›
Chains: E, F
Length: 6 amino acids
Theoretical weight: 687 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 6 amino acids
Theoretical weight: 687 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P18754 (Residues: 2-7; Coverage: 1%)
