Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-219660 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Set1/Ash2 histone methyltransferase complex subunit ASH2
Molecule details ›
Chain: D
Length: 214 amino acids
Theoretical weight: 23.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: SPRY domain
Length: 214 amino acids
Theoretical weight: 23.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9UBL3 (Residues: 380-622; Coverage: 33%)
Sequence domains: SPRY domain
Protein dpy-30 homolog
Molecule details ›
Chains: E, F
Length: 100 amino acids
Theoretical weight: 11.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Dpy-30 motif
Structure domains: cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
Length: 100 amino acids
Theoretical weight: 11.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9C005 (Residues: 1-99; Coverage: 100%)
Sequence domains: Dpy-30 motif
Structure domains: cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 17-ID
Spacegroup:
P43212
Expression system: Escherichia coli
