6ehg

X-ray diffraction
2.65Å resolution

complement component C3b in complex with a nanobody

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-208329 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Complement C3 beta chain Chain: A
Molecule details ›
Chain: A
Length: 643 amino acids
Theoretical weight: 71.27 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01024 (Residues: 23-665; Coverage: 39%)
Gene names: C3, CPAMD1
Sequence domains:
Structure domains:
hC3Nb1 Chain: C
Molecule details ›
Chain: C
Length: 130 amino acids
Theoretical weight: 14.35 KDa
Source organism: Lama glama
Expression system: Escherichia coli

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: P21212
Unit cell:
a: 255.31Å b: 64.88Å c: 144.72Å
α: 90° β: 90° γ: 90°
Expression system: Escherichia coli