› 6f27

Solution NMR

NMR solution structure of non-bound [des-Arg10]-kallidin (DAKD)

Released:
DOI: 10.2210/pdb6f27/pdb
PDB entry 6f27 coloured by chain, ensemble of 20 models, front view.
PDB entry 6f27 coloured by chain, ensemble of 20 models, side view.
PDB entry 6f27 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors.
Joedicke L, Mao J, Kuenze G, Reinhart C, Kalavacherla T, Jonker HRA, Richter C, Schwalbe H, Meiler J, Preu J, Michel H, Glaubitz C
Nat Chem Biol 14 284-290 (2018)
PMID: 29334381

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133899 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bradykinin Chain: A
Molecule details ›
Chain: A
Length: 9 amino acids
Theoretical weight: 1.03 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01042 (Residues: 380-388; Coverage: 1%)
Gene names: BDK, KNG, KNG1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 87%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

10 review citations

GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures.
Shimada et al. (2019)
9 more

1 mention without citation

High Molecular Weight Kininogen: A Review of the Structural Literature.
Ponczek MB. (2021)