6f6p

X-ray diffraction
2.45Å resolution

Crystal structure of tetrameric human Rabin8 GEF domain

Released:

Function and Biology Details

Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-188700 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rab-3A-interacting protein Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 106 amino acids
Theoretical weight: 11.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96QF0 (Residues: 159-261; Coverage: 22%)
Gene names: RAB3IP, RABIN8
Sequence domains: GDP/GTP exchange factor Sec2p
Rab-3A-interacting protein Chain: C
Molecule details ›
Chain: C
Length: 106 amino acids
Theoretical weight: 12.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96QF0 (Residues: 159-261; Coverage: 22%)
Gene names: RAB3IP, RABIN8
Sequence domains: GDP/GTP exchange factor Sec2p

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: P212121
Unit cell:
a: 47.322Å b: 77Å c: 137.258Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.273 0.271 0.305
Expression system: Escherichia coli