› 6fqf

X-ray diffraction
2.1Å resolution

THE X-RAY STRUCTURE OF FERRIC-BETA4 HUMAN HEMOGLOBIN

Released:
DOI: 10.2210/pdb6fqf/pdb
PDB entry 6fqf coloured by chain, front view.
PDB entry 6fqf coloured by chain, side view.
PDB entry 6fqf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the ferric homotetrameric β4 human hemoglobin.
Mazzarella L, Merlino A, Balasco N, Balsamo A, Vergara A
Biophys Chem 240 9-14 (2018)
PMID: 29857171

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159525 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemoglobin subunit beta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 146 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:
Ligand HEM 4 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P21
Unit cell:
a: 52.7Å b: 82.1Å c: 62.5Å
α: 90° β: 91.3° γ: 90°
R-values:
R R work R free
0.207 0.204 0.265
Expression system: Escherichia coli K-12

Quick links

Citations

1 citations in other articles

The unique structural features of carbonmonoxy hemoglobin from the sub-Antarctic fish Eleginops maclovinus.
Balasco et al. (2019)