› 6gtt

X-ray diffraction
2.25Å resolution

Human STK10 bound to BIRB-796

Released:
DOI: 10.2210/pdb6gtt/pdb
PDB entry 6gtt coloured by chain, front view.
PDB entry 6gtt coloured by chain, side view.
PDB entry 6gtt coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Berger BT, Sorrell FJ, von Delft F, Bountra C, Knapp S, Edwards AM, Arrowsmith C, Elkins JM

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131759 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase 10 Chain: A
Molecule details ›
Chain: A
Length: 302 amino acids
Theoretical weight: 34.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O94804 (Residues: 18-317; Coverage: 31%)
Gene names: LOK, STK10
Sequence domains: Protein kinase domain

Ligands and Environments

1 bound ligand:
Ligand B96 1 x B96
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6422
Unit cell:
a: 100.667Å b: 100.667Å c: 145.786Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.24 0.301
Expression system: Escherichia coli BL21(DE3)

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