Function and Biology Details
Reaction catalysed:
ATP + H(2)O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146640 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein beta/alpha
Molecule details ›
Chains: A, B, C, D
Length: 235 amino acids
Theoretical weight: 26.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Length: 235 amino acids
Theoretical weight: 26.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P31946 (Residues: 1-232; Coverage: 94%)
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Cystic fibrosis transmembrane conductance regulator
Molecule details ›
Chains: E, F
Length: 28 amino acids
Theoretical weight: 3.26 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 28 amino acids
Theoretical weight: 3.26 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P13569 (Residues: 747-774; Coverage: 2%)
