Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134183 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Insulin A chain
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical:
P01308 (Residues: 90-110; Coverage: 24%)
Insulin B chain
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Sequence domains: Insulin/IGF/Relaxin family
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P01308 (Residues: 25-54; Coverage: 35%)
Sequence domains: Insulin/IGF/Relaxin family
General control transcription factor GCN4; Insulin receptor subunit alpha
Molecule details ›
Chains: E, F
Length: 930 amino acids
Theoretical weight: 106.73 KDa
Source organisms: Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Length: 930 amino acids
Theoretical weight: 106.73 KDa
Source organisms: Expression system: Cricetulus griseus
UniProt:
- Canonical: P06213 (Residues: 28-955; Coverage: 66%)
- Canonical: P03069 (Residues: 249-281; Coverage: 12%)
Sequence domains:
