Function and Biology Details
Reaction catalysed:
(S)-3-hydroxybutanoyl-CoA + NADP(+) = 3-acetoacetyl-CoA + NADPH
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- 6-phosphogluconate dehydrogenase, domain 2
- 3-hydroxyacyl-CoA dehydrogenase, C-terminal
- 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
- 3-hydroxyacyl-CoA dehydrogenase, conserved site
- 3-hydroxyacyl-CoA dehydrogenase, NAD binding
- NAD(P)-binding domain superfamily
- 3-hydroxyacyl-CoA dehydrogenase
Structure analysis Details
Assembly composition:
homo hexamer (preferred)
Assembly name:
3-hydroxybutyryl-CoA dehydrogenase (preferred)
PDBe Complex ID:
PDB-CPX-156457 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-hydroxybutyryl-CoA dehydrogenase
Molecule details ›
Chains: A, B, C, D, E, F
Length: 302 amino acids
Theoretical weight: 32.79 KDa
Source organism: Clostridium acetobutylicum ATCC 824
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 302 amino acids
Theoretical weight: 32.79 KDa
Source organism: Clostridium acetobutylicum ATCC 824
Expression system: Escherichia coli
UniProt:
- Canonical:
P52041 (Residues: 1-282; Coverage: 100%)
Sequence domains:
- 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
- 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
