6al5

X-ray diffraction
3Å resolution

COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-108707 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
B-lymphocyte antigen CD19 Chain: A
Molecule details ›
Chain: A
Length: 265 amino acids
Theoretical weight: 29.3 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P15391 (Residues: 21-277; Coverage: 48%)
Gene name: CD19
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 218 amino acids
Theoretical weight: 23.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6P5S8 (Residues: 21-49, 50-51, 52-236; Coverage: 100%)
Gene name: IGK@
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chain: H
Molecule details ›
Chain: H
Length: 233 amino acids
Theoretical weight: 25.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: A8K008 (Residues: 20-70, 71-118, 119-245; Coverage: 49%)
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 64.8Å b: 92.35Å c: 146.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.189 0.263
Expression systems:
  • unidentified baculovirus
  • Homo sapiens