› 6az0

Electron Microscopy
3.4Å resolution

Mitochondrial ATPase Protease YME1

Released:
DOI: 10.2210/pdb6az0/pdb
PDB entry 6az0 coloured by chain, ensemble of 5 models, front view.
PDB entry 6az0 coloured by chain, ensemble of 5 models, side view.
PDB entry 6az0 coloured by chain, ensemble of 5 models, top view.
Source organisms:
Primary publication:
Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing.
Puchades C, Rampello AJ, Shin M, Giuliano CJ, Wiseman RL, Glynn SE, Lander GC
Science 358 (2017)
PMID: 29097521
Related structures: EMD-7023

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109879 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
AAA+ ATPase domain-containing protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 439 amino acids
Theoretical weight: 48.03 KDa
Source organism: Saccharomyces cerevisiae RM11-1a
Expression system: Escherichia coli
UniProt:
  • Canonical: B3LL85 (Residues: 279-717; Coverage: 59%)
Gene name: SCRG_02514
Sequence domains:
Structure domains:
poly(UNK) Chain: G
Molecule details ›
Chain: G
Length: 10 amino acids
Theoretical weight: 869 Da
Source organism: Escherichia coli

Ligands and Environments

4 bound ligands:
Ligand ATP 4 x ATP
Ligand ZN 6 x ZN
Ligand MG 4 x MG
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-7023
Expression system: Escherichia coli

Quick links

Citations

29 review citations

Mitochondrial proteins: from biogenesis to functional networks.
Pfanner et al. (2019)
28 more

14 mentions without citation

The molecular principles governing the activity and functional diversity of AAA+ proteins.
Puchades et al. (2020)
13 more