6b1t

Electron Microscopy
3.2Å resolution

Improved cryoEM structure of human adenovirus type 5 with atomic details of minor proteins VI and VII

Released:
Source organism: Human adenovirus 5
Primary publication:
Atomic Structures of Minor Proteins VI and VII in Human Adenovirus.
J Virol 91 (2017)
PMID: 28978703
Related structures: EMD-7034

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 1500-mer (preferred)
PDBe Complex ID:
PDB-CPX-136684 (preferred)
Entry contents:
8 distinct polypeptide molecules
Macromolecules (8 distinct):
Hexon protein Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 952 amino acids
Theoretical weight: 108.11 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P04133 (Residues: 1-952; Coverage: 100%)
Gene name: L3
Sequence domains:
Penton protein Chain: M
Molecule details ›
Chain: M
Length: 571 amino acids
Theoretical weight: 63.36 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P12538 (Residues: 1-571; Coverage: 100%)
Gene name: L2
Sequence domains: Adenovirus penton base protein
Pre-hexon-linking protein IIIa Chain: N
Molecule details ›
Chain: N
Length: 585 amino acids
Theoretical weight: 65.32 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P12537 (Residues: 1-585; Coverage: 100%)
Gene name: L1
Sequence domains: Hexon-associated protein (IIIa)
Pre-hexon-linking protein VIII Chains: O, P
Molecule details ›
Chains: O, P
Length: 227 amino acids
Theoretical weight: 24.71 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P24936 (Residues: 1-227; Coverage: 100%)
Gene name: L4
Sequence domains: Adenovirus hexon associated protein, protein VIII
Hexon-interlacing protein Chains: Q, R, S, T
Molecule details ›
Chains: Q, R, S, T
Length: 140 amino acids
Theoretical weight: 14.47 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P03281 (Residues: 1-140; Coverage: 100%)
Gene name: IX
Sequence domains: Adenovirus hexon-associated protein (IX)
Pre-protein VI Chains: U, V, Y
Molecule details ›
Chains: U, V, Y
Length: 33 amino acids
Theoretical weight: 3.58 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P24937 (Residues: 1-33; Coverage: 13%)
Gene name: L3
Pre-histone-like nucleoprotein Chain: W
Molecule details ›
Chain: W
Length: 11 amino acids
Theoretical weight: 1.2 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P68951 (Residues: 14-24; Coverage: 6%)
Gene name: L2
Endosome lysis protein Chain: X
Molecule details ›
Chain: X
Length: 217 amino acids
Theoretical weight: 23.46 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P24937 (Residues: 34-250; Coverage: 87%)
Gene name: L3
Sequence domains: Minor capsid protein VI

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-7034