6brb

X-ray diffraction
2.82Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-150295 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
CD40 ligand, soluble form Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 15.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P29965 (Residues: 120-261; Coverage: 54%)
Gene names: CD40L, CD40LG, TNFSF5, TRAP
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Tenascin Chain: D
Molecule details ›
Chain: D
Length: 87 amino acids
Theoretical weight: 9.88 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P24821 (Residues: 809-893; Coverage: 4%)
Gene names: HXB, TNC
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P321
Unit cell:
a: 93.528Å b: 93.528Å c: 66.685Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.225 0.273
Expression systems:
  • Homo sapiens
  • Escherichia coli