Protein Data Bank in Europe

Chains: A, B
Length: 347 amino acids
Theoretical weight: 37.75 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:

• Canonical: P9WGZ1 (Residues: 1-347; Coverage: 100%)

Gene names: MTCY13E12.10c, Rv3457c, rpoA
Sequence domains:

• RNA polymerase Rpb3/Rpb11 dimerisation domain
• RNA polymerase Rpb3/RpoA insert domain
• Bacterial RNA polymerase, alpha chain C terminal domain

Structure domains:

• RNA polymerase, RBP11-like subunit
• DNA-directed RNA polymerase, insert domain

Chain: C
Length: 1179 amino acids
Theoretical weight: 130.07 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:

• Canonical: P9WGY9 (Residues: 7-1178; Coverage: 100%)

Gene names: MTCI376.08c, Rv0667, rpoB
Sequence domains:

• RNA polymerase beta subunit
• RNA polymerase Rpb2, domain 2
• RNA polymerase Rpb2, domain 3
• RNA polymerase beta subunit external 1 domain
• RNA polymerase Rpb2, domain 6
• RNA polymerase Rpb2, domain 7

Chain: D
Length: 1326 amino acids
Theoretical weight: 148.2 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:

• Canonical: P9WGY7 (Residues: 1-1316; Coverage: 100%)

Gene names: MTCI376.07c, Rv0668, rpoC
Sequence domains:

• RNA polymerase Rpb1, domain 1
• RNA polymerase Rpb1, domain 2
• RNA polymerase Rpb1, domain 3
• RNA polymerase Rpb1, domain 4
• RNA polymerase Rpb1, domain 5

Chain: E
Length: 110 amino acids
Theoretical weight: 11.78 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:

• Canonical: P9WGY5 (Residues: 2-110; Coverage: 99%)

Gene names: MTCY21B4.07, Rv1390, rpoZ
Sequence domains: RNA polymerase Rpb6

Chain: F
Length: 531 amino acids
Theoretical weight: 58.17 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:

• Canonical: P9WGI1 (Residues: 1-528; Coverage: 100%)

Gene names: MTCY05A6.24, Rv2703, mysA, rpoD, rpoV, sigA
Sequence domains:

• Sigma-70 factor, region 1.2
• Sigma-70 region 2
• Sigma-70 region 3
• Sigma-70, region 4

Chain: J
Length: 111 amino acids
Theoretical weight: 12.99 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:

• Canonical: P9WHJ5 (Residues: 1-111; Coverage: 100%)

Gene names: Rv2050, rbpA
Sequence domains: RNA polymerase-binding protein

Chains: H, O
Length: 31 nucleotides
Theoretical weight: 9.57 KDa

Chains: G, P
Length: 26 nucleotides
Theoretical weight: 7.93 KDa