› 6c53

Electron Microscopy
4.2Å resolution

Cryo-EM structure of the Type 1 pilus rod

Released:
DOI: 10.2210/pdb6c53/pdb
PDB entry 6c53 coloured by chain, front view.
PDB entry 6c53 coloured by chain, side view.
PDB entry 6c53 coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions.
Spaulding CN, Schreiber HL, Zheng W, Dodson KW, Hazen JE, Conover MS, Wang F, Svenmarker P, Luna-Rico A, Francetic O, Andersson M, Hultgren S, Egelman EH
Elife 7 (2018)
PMID: 29345620
Related structures: EMD-7342

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo undecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137420 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type-1 fimbrial protein, A chain Chains: A, B, C, D, E, F, G, H, I, J, K
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K
Length: 159 amino acids
Theoretical weight: 15.84 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P04128 (Residues: 24-182; Coverage: 100%)
Gene names: JW4277, b4314, fimA, pilA
Sequence domains: Fimbrial protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.2Å
Relevant EMDB volumes: EMD-7342

Quick links

Citations

5 review citations

Urinary tract infections: microbial pathogenesis, host-pathogen interactions and new treatment strategies.
Klein et al. (2020)
4 more

2 mentions without citation

Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions.
Spaulding et al. (2018)
1 more