Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
Insulin complex (preferred)
PDBe Complex ID:
PDB-CPX-134196 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Insulin receptor subunit alpha
Molecule details ›
Chains: A, B
Length: 929 amino acids
Theoretical weight: 105.93 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
Sequence domains:
Length: 929 amino acids
Theoretical weight: 105.93 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
- Canonical:
P06213 (Residues: 28-956; Coverage: 69%)
Sequence domains:
Insulin A chain
Molecule details ›
Chain: N
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Insulin B chain
Molecule details ›
Chain: O
Length: 30 amino acids
Theoretical weight: 3.4 KDa
Source organism: Ovis aries
Expression system: Not provided
UniProt:
Sequence domains: Insulin/IGF/Relaxin family
Length: 30 amino acids
Theoretical weight: 3.4 KDa
Source organism: Ovis aries
Expression system: Not provided
UniProt:
- Canonical: P01318 (Residues: 25-54; Coverage: 37%)
Sequence domains: Insulin/IGF/Relaxin family
Insulin receptor subunit alpha
Molecule details ›
Chain: P
Length: 30 amino acids
Theoretical weight: 3.67 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
Length: 30 amino acids
Theoretical weight: 3.67 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
- Canonical: P06213 (Residues: 718-746; Coverage: 2%)
