› 6cok

X-ray diffraction
1.89Å resolution

Structure of the 2nd TOG domain from yeast CLASP protein STU1

Released:
DOI: 10.2210/pdb6cok/pdb
PDB entry 6cok coloured by chain, front view.
PDB entry 6cok coloured by chain, side view.
PDB entry 6cok coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
An isolated CLASP TOG domain suppresses microtubule catastrophe and promotes rescue.
Majumdar S, Kim T, Chen Z, Munyoki S, Tso SC, Brautigam CA, Rice LM
Mol Biol Cell 29 1359-1375 (2018)
PMID: 29851564

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153575 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein STU1 Chain: A
Molecule details ›
Chain: A
Length: 320 amino acids
Theoretical weight: 36.86 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P38198 (Residues: 249-567; Coverage: 21%)
Gene names: STU1, YBL034C, YBL0416
Sequence domains: CLASP N terminal

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 31.412Å b: 111.009Å c: 44.937Å
α: 90° β: 101.36° γ: 90°
R-values:
R R work R free
0.175 0.173 0.212
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Regulation of microtubule dynamics, mechanics and function through the growing tip.
Gudimchuk et al. (2021)
5 more

2 mentions without citation

MAPping tubulin mutations.
Cushion et al. (2023)
1 more